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  • 2025
    Postal J, Guivel-Benhassine F, Porrot F, Grassin Q, Crook JM, Vernuccio R, Caro V, Vanhomwegen J, Guardado-Calvo P, Simon-Lorière E, Dacheux L, Manuguerra JC, Schwartz O, Antiviral activity of tecovirimat against monkeypox virus clades 1a, 1b, 2a, and 2b., Lancet Infect Dis 2025 Jan; (): .
  • 2025
    Riccardo Vernuccio, Alejandro Martínez León, Chetan Poojari, Julian Buchrieser, Christopher Selverian, Yakin Jaleta, Annalisa Meola, Florence Guivel-Benhassine, Françoise Porrot, Ahmed Haouz, Maelenn Chevreuil, Bertrand Raynal, Jason Mercer, Etienne Simon-Loriere, Kartik Chandran, Olivier Schwartz, Jochen Hub, Pablo Guardado-Calvo, Structural insights into tecovirimat antiviral activity and poxvirus resistance, Nature Microbiology, In press, ⟨10.1038/s41564-025-01936-6⟩.
  • 2024
    Vernuccio R, León AM, Poojari CS, Buchrieser J, Selverian C, Jaleta Y, Meola A, Guivel-Benhassine F, Porrot F, Haouz A, Chevreuil M, Raynal B, Mercer J, Simon-Loriere E, Chandran K, Schwartz O, Hub JS, Guardado-Calvo P, MECHANISMS OF TECOVIRIMAT ANTIVIRAL ACTIVITY AND POXVIRUS RESISTANCE., Res Sq 2024 Sep; (): .
  • 2024
    Meola A, Guardado-Calvo P, Production and Purification of Hantavirus Glycoproteins in Drosophila melanogaster S2 Cells., Methods Mol Biol 2024 ; 2762(): 3-16.
  • 2023
    Vernuccio Riccardo, Guardado-Calvo Pablo, Neutralization Determinants on Poxviruses, Viruses, 2023, 15 (12), pp.2396. ⟨10.3390/v15122396⟩.
  • 2023
    Slough MM, Li R, Herbert AS, Lasso G, Kuehne AI, Monticelli SR, Bakken RR, Liu Y, Ghosh A, Moreau AM, Zeng X, Rey FA, Guardado-Calvo P, Almo SC, Dye JM, Jangra RK, Wang Z, Chandran K, Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection., Nat Commun 2023 Jul; 14(1): 4454.
  • 2023
    Mittler E, Serris A, Esterman ES, Florez C, Polanco LC, O'Brien CM, Slough MM, Tynell J, Gröning R, Sun Y, Abelson DM, Wec AZ, Haslwanter D, Keller M, Ye C, Bakken RR, Jangra RK, Dye JM, Ahlm C, Rappazzo CG, Ulrich RG, Zeitlin L, Geoghegan JC, Bradfute SB, Sidoli S, Forsell MNE, Strandin T, Rey FA, Herbert AS, Walker LM, Chandran K, Guardado-Calvo P, Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody., Sci Transl Med 2023 Jun; 15(700): eadg1855.
  • 2023
    Hellert J, Aebischer A, Haouz A, Guardado-Calvo P, Reiche S, Beer M, Rey FA, Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein., Cell Rep 2023 Mar; 42(3): 112142.
  • 2023
    Engdahl TB, Binshtein E, Brocato RL, Kuzmina NA, Principe LM, Kwilas SA, Kim RK, Chapman NS, Porter MS, Guardado-Calvo P, Rey FA, Handal LS, Diaz SM, Zagol-Ikapitte IA, Tran MH, McDonald WH, Meiler J, Reidy JX, Trivette A, Bukreyev A, Hooper JW, Crowe JE, Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies., Elife 2023 Mar; 12(): .
  • 2023
    Bratuleanu BE, Raileanu C, Chrétien D, Guardado-Calvo P, Bigot T, Savuta G, Temmam S, Eloit M, A Search for Tick-Associated, Bronnoya-like Virus Spillover into Sheep., Microorganisms 2023 Jan; 11(1): .
  • 2022
    Planchais C, Fernández I, Bruel T, de Melo GD, Prot M, Beretta M, Guardado-Calvo P, Dufloo J, Molinos-Albert LM, Backovic M, Chiaravalli J, Giraud E, Vesin B, Conquet L, Grzelak L, Planas D, Staropoli I, Guivel-Benhassine F, Hieu T, Boullé M, Cervantes-Gonzalez M, Ungeheuer MN, Charneau P, van der Werf S, Agou F, , , Dimitrov JD, Simon-Lorière E, Bourhy H, Montagutelli X, Rey FA, Schwartz O, Mouquet H, Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2., J Exp Med 2022 Jul; 219(7): .
  • 2022
    Mittler E, Wec AZ, Tynell J, Guardado-Calvo P, Wigren-Byström J, Polanco LC, O'Brien CM, Slough MM, Abelson DM, Serris A, Sakharkar M, Pehau-Arnaudet G, Bakken RR, Geoghegan JC, Jangra RK, Keller M, Zeitlin L, Vapalahti O, Ulrich RG, Bornholdt ZA, Ahlm C, Rey FA, Dye JM, Bradfute SB, Strandin T, Herbert AS, Forsell MNE, Walker LM, Chandran K, , Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses., Sci Transl Med 2022 Mar; 14(636): eabl5399.
  • 2022
    Mishra AK, Hellert J, Freitas N, Guardado-Calvo P, Haouz A, Fels JM, Maurer DP, Abelson DM, Bornholdt ZA, Walker LM, Chandran K, Cosset FL, McLellan JS, Rey FA, Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies., Science 2022 Jan; 375(6576): 104-109.
  • 2022
    Jangra RK, Llabrés M, Guardado-Calvo P, Mittler E, Lasso G, , Editorial: Influence of Protein-Protein Interactions (PPIs) on the Outcome of Viral Infections., Front Microbiol 2022 ; 13(): 943379.
  • 2021
    Sharma A, Zhang X, Dejnirattisai W, Dai X, Gong D, Wongwiwat W, Duquerroy S, Rouvinski A, Vaney MC, Guardado-Calvo P, Haouz A, England P, Sun R, Zhou ZH, Mongkolsapaya J, Screaton GR, Rey FA, , The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses., Cell 2021 Dec; 184(25): 6052-6066.e18.
  • 2021
    Guardado-Calvo P, Rey FA, , The Viral Class II Membrane Fusion Machinery: Divergent Evolution from an Ancestral Heterodimer., Viruses 2021 Nov; 13(12): .
  • 2021
    Guardado-Calvo P, Rey FA, , The surface glycoproteins of hantaviruses., Curr Opin Virol 2021 Oct; 50(): 87-94.
  • 2021
    Light TP, Brun D, Guardado-Calvo P, Pederzoli R, Haouz A, Neipel F, Rey FA, Hristova K, Backovic M, , Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling., PLoS Biol 2021 Sep; 19(9): e3001392.
  • 2021
    Kerkman PF, Dernstedt A, Tadala L, Mittler E, Dannborg M, Sundling C, Maleki KT, Tauriainen J, Tuiskunen-Bäck A, Wigren Byström J, Ocaya P, Thunberg T, Jangra RK, Román-Sosa G, Guardado-Calvo P, Rey FA, Klingström J, Chandran K, Puhar A, Ahlm C, Forsell MN, , Generation of plasma cells and CD27-IgD- B cells during hantavirus infection is associated with distinct pathological findings., Clin Transl Immunology 2021 ; 10(7): e1313.
  • 2020
    Serris A, Stass R, Bignon EA, Muena NA, Manuguerra JC, Jangra RK, Li S, Chandran K, Tischler ND, Huiskonen JT, Rey FA, Guardado-Calvo P, , The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism., Cell 2020 Oct; 183(2): 442-456.e16.
  • 2020
    Wichgers Schreur PJ, van de Water S, Harmsen M, Bermúdez-Méndez E, Drabek D, Grosveld F, Wernike K, Beer M, Aebischer A, Daramola O, Rodriguez Conde S, Brennan K, Kozub D, Søndergaard Kristiansen M, Mistry KK, Deng Z, Hellert J, Guardado-Calvo P, Rey FA, van Keulen L, Kortekaas J, , Multimeric single-domain antibody complexes protect against bunyavirus infections., Elife 2020 Apr; 9(): .
  • 2019
    Bignon EA, Albornoz A, Guardado-Calvo P, Rey FA, Tischler ND, , Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface., Elife 2019 Jun; 8(): .
  • 2019
    Hellert J, Aebischer A, Wernike K, Haouz A, Brocchi E, Reiche S, Guardado-Calvo P, Beer M, Rey FA, , Orthobunyavirus spike architecture and recognition by neutralizing antibodies., Nat Commun 2019 Feb; 10(1): 879.
  • 2019
    Dorgham K, Pietrancosta N, Affoune A, Lucar O, Bouceba T, Chardonnet S, Pionneau C, Piesse C, Sterlin D, Guardado-Calvo P, Karoyan P, Debré P, Gorochov G, Vieillard V, , Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope., J Immunol Res 2019 ; 2019(): 9804584.
  • 2018
    Jangra RK, Herbert AS, Li R, Jae LT, Kleinfelter LM, Slough MM, Barker SL, Guardado-Calvo P, Román-Sosa G, Dieterle ME, Kuehne AI, Muena NA, Wirchnianski AS, Nyakatura EK, Fels JM, Ng M, Mittler E, Pan J, Bharrhan S, Wec AZ, Lai JR, Sidhu SS, Tischler ND, Rey FA, Moffat J, Brummelkamp TR, Wang Z, Dye JM, Chandran K, , Protocadherin-1 is essential for cell entry by New World hantaviruses., Nature 2018 Nov; 563(7732): 559-563.
  • 2018
    Vallbracht M, Brun D, Tassinari M, Vaney MC, Pehau-Arnaudet G, Guardado-Calvo P, Haouz A, Klupp BG, Mettenleiter TC, Rey FA, Backovic M, , Structure-Function Dissection of Pseudorabies Virus Glycoprotein B Fusion Loops., J Virol 2018 Jan; 92(1): .
  • 2017
    Guardado-Calvo P, Atkovska K, Jeffers SA, Grau N, Backovic M, Pérez-Vargas J, de Boer SM, Tortorici MA, Pehau-Arnaudet G, Lepault J, England P, Rottier PJ, Bosch BJ, Hub JS, Rey FA, , A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion., Science 2017 Nov; 358(6363): 663-667.
  • 2017
    Rouvinski A, Dejnirattisai W, Guardado-Calvo P, Vaney MC, Sharma A, Duquerroy S, Supasa P, Wongwiwat W, Haouz A, Barba-Spaeth G, Mongkolsapaya J, Rey FA, Screaton GR, , Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope., Nat Commun 2017 May; 8(): 15411.
  • 2017
    Guardado-Calvo P, Rey FA, , The Envelope Proteins of the Bunyavirales., Adv Virus Res 2017 ; 98(): 83-118.
  • 2016
    Guardado-Calvo P, Bignon EA, Stettner E, Jeffers SA, Pérez-Vargas J, Pehau-Arnaudet G, Tortorici MA, Jestin JL, England P, Tischler ND, Rey FA, , Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc., PLoS Pathog 2016 Oct; 12(10): e1005813.
  • 2015
    Rouvinski A, Guardado-Calvo P, Barba-Spaeth G, Duquerroy S, Vaney MC, Kikuti CM, Navarro Sanchez ME, Dejnirattisai W, Wongwiwat W, Haouz A, Girard-Blanc C, Petres S, Shepard WE, Desprès P, Arenzana-Seisdedos F, Dussart P, Mongkolsapaya J, Screaton GR, Rey FA, , Recognition determinants of broadly neutralizing human antibodies against dengue viruses., Nature 2015 Apr; 520(7545): 109-13.
  • 2014
    Meola A, Deville C, Jeffers SA, Guardado-Calvo P, Vasiliauskaite I, Sizun C, Girard-Blanc C, Malosse C, van Heijenoort C, Chamot-Rooke J, Krey T, Guittet E, Pêtres S, Rey FA, Bontems F, , Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications., J Struct Biol 2014 Oct; 188(1): 71-8.
  • 2012
    Otero JM, Noël AJ, Guardado-Calvo P, Llamas-Saiz AL, Wende W, Schierling B, Pingoud A, van Raaij MJ, , High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan., Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Oct; 68(Pt 10): 1139-48.
  • 2010
    Guardado-Calvo P, Muñoz EM, Llamas-Saiz AL, Fox GC, Kahn R, Curiel DT, Glasgow JN, van Raaij MJ, , Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains., J Virol 2010 Oct; 84(20): 10558-68.
  • 2010
    Prazeres VF, Tizón L, Otero JM, Guardado-Calvo P, Llamas-Saiz AL, van Raaij MJ, Castedo L, Lamb H, Hawkins AR, González-Bello C, , Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues., J Med Chem 2010 Jan; 53(1): 191-200.
  • 2009
    Guardado-Calvo P, Llamas-Saiz AL, Fox GC, Glasgow JN, van Raaij MJ, , Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibre., Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 Nov; 65(Pt 11): 1149-52.
  • 2009
    Guardado-Calvo P, Fox GC, Llamas-Saiz AL, van Raaij MJ, , Crystallographic structure of the alpha-helical triple coiled-coil domain of avian reovirus S1133 fibre., J Gen Virol 2009 Mar; 90(Pt 3): 672-677.
  • 2008
    Guardado-Calvo P, Vazquez-Iglesias L, Martinez-Costas J, Llamas-Saiz AL, Schoehn G, Fox GC, Hermo-Parrado XL, Benavente J, van Raaij MJ, , Crystal structure of the avian reovirus inner capsid protein sigmaA., J Virol 2008 Nov; 82(22): 11208-16.
  • 2007
    Guardado-Calvo P, Llamas-Saiz AL, Fox GC, Langlois P, van Raaij MJ, , Structure of the C-terminal head domain of the fowl adenovirus type 1 long fiber., J Gen Virol 2007 Sep; 88(Pt 9): 2407-2416.
  • 2007
    Hermo-Parrado XL, Guardado-Calvo P, Llamas-Saiz AL, Fox GC, Vazquez-Iglesias L, Martínez-Costas J, Benavente J, van Raaij MJ, , Crystallization of the avian reovirus double-stranded RNA-binding and core protein sigmaA., Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 May; 63(Pt 5): 426-9.
  • 2006
    Guardado Calvo P, Llamas-Saiz AL, Langlois P, van Raaij MJ, , Crystallization of the C-terminal head domain of the avian adenovirus CELO long fibre., Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 May; 62(Pt 5): 449-52.
  • 2005
    Guardado Calvo P, Fox GC, Hermo Parrado XL, Llamas-Saiz AL, Costas C, Martínez-Costas J, Benavente J, van Raaij MJ, , Structure of the carboxy-terminal receptor-binding domain of avian reovirus fibre sigmaC., J Mol Biol 2005 Nov; 354(1): 137-49.
  • 2005
    van Raaij MJ, Hermo Parrado XL, Guardado Calvo P, Fox GC, Llamas-Saiz AL, Costas C, Martínez-Costas J, Benavente J, , Crystallization of the C-terminal globular domain of avian reovirus fibre., Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 Jul; 61(Pt 7): 651-4.
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